Mannatech has announced the results of an independent study demonstrating that our proprietary Ambrotose® complex and Advanced Ambrotose® powder exerted prebiotic effects.* † The study was conducted by scientists at Ghent University and ProDigest, a leading company in gastrointestinal (GI) research.
The study, conducted at a top European research institute in Belgium, investigated the effects of Ambrotose complex and Advanced Ambrotose powder on the structure, composition and metabolism of the human GI tract using state-of-the-art human GI tract simulations and sophisticated microbiological analyses.
Its findings determined both Ambrotose complex and Advanced Ambrotose powder exhibited good selective fermentability throughout the entire colon, positive and selective bifidogenic effects and also demonstrated the possibility of enhancing species belonging to Bacteroidetes.
"We have been interested in the effects of Ambrotose products on GI health-a very hot area of scientific research-for many years," said Mannatech's Co-CEO and Chief Science Officer, Robert A. Sinnott, MNS, Ph.D. "A preliminary study published in 2007 showed that these products function as prebiotics, but the human gut is incredibly complex and difficult to study. To learn more, we chose to rely on the expertise of researchers on the forefront of human GI research. The work done by Dr. Marzorati and his team suggests that Ambrotose products support GI health throughout the entire colon; most prebiotics are thought to only exert such effects in the first portion of the colon."
The study's findings were published in the peer‐reviewed International Journal of Food Microbiologyand indexed on PubMed by Drs. Massimo Marzorati and Sam Possemiers (U. of Ghent and ProDigest), A. Verhelst (ProDigest), Profs. Willy Verstraete and T. Van de Wiele (U. of Ghent) and Drs. Robert Sinnott and Gabriela Luta (Mannatech, Incorporated).
"We are intensely interested in employing state-of-the-art technology to explore the effects of our Ambrotose products," said Sinnott. "This study provides important information about the activities of these products in the human GI tract."